ZANAMIVIR HYDRATE CAS No.139110-80-8
Product Name: ZANAMIVIR HYDRATE
Full English
name:3-acetamido-4-(diaminomethylideneamino)-2-(1,2,3-trihydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxylic
acid hydrate
Chemical name: (2R, 3R, 4S) - 3-acetylamino-4 -
(aminoiminomethylamino) - 2 - [(1R, 2R) - 1,2,3-trihydroxypropyl] -
3,4-dihydro-2h-pyran-6-carboxylic acid
CAS No:139110-80-8
Molecular formula : C12H20N4O7
Molecular weight : 332.31
Physical and chemical properties:
Colorless crystal, melting point > 240 ℃ (decomposition), [α]
D20 + 41.0 ° (C = 0.9, H2O), soluble in water, density 1.75 ±
0.1g/cm3
Product category:
Zanamivir is a kind of anti influenza virus drug developed by biota
company in Australia. It was marketed in the UK in 1999. Its trade
name is Relenza. Zanamivir is a neuraminidase inhibitor. It can
change the aggregation and release of influenza virus in infected
cells by inhibiting neuraminidase of influenza virus. Neuraminidase
is the key enzyme of respiratory virus replication, which can break
the chemical bond between sialic acid and cell surface protein, so
as to separate the newly generated virus particles from the
infected cells, and then infect the nearby normal cells. Inhibition
of neuraminidase can prevent the virus from spreading to other
cells in the respiratory tract. This product can be used to treat
and prevent the spread of influenza virus in the respiratory tract,
and it is very effective within 48 hours after the onset of
symptoms. This product is a dry powder inhaler, distributed in the
respiratory tract after inhalation, such as nasopharynx, which can
effectively inhibit neuraminidase activity. Oral administration of
this product is invalid.
